Clicio
Masterpiece
Yes you can! I've had little issue with the floating, I mean yes it will tend to 'rise' to the top in the highest inch or two of substrate but this isn't anything that bothers me as I'm developing trees so the aesthetics of my substrate is of zero consequence (I wouldn't advise perlite for showing a tree of course, but for growing it's great stuff!)
Thanks for sharing your helpful experience, @SU2 , I will consider using it in a mix with relatively high proportion of organics.